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--- jc [2024/05/14 17:56] – admin
+++ jc [2026/03/31 14:20] (current) – admin
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 ===== Ideas =====
-  * [[https://doi.org/10.1056/NEJMoa2312572 | DANGER-SHOCK]]
+  * Airway
-    * **Finding**: Impella CP reduces mortality
+    * [[https://doi.org/10.1001/jama.2024.0762 | Hyperangulated VL vs Standard DL in Surgical Patients]]
-    * **Significance**: First trial to show mortality benefit from MCS
+      * **Finding**: First-pass intubation failure: hyperangulated VL 1.7% vs DL 7.6%
-  * [[https://doi.org/10.1001/jama.2024.0762 | Hyperangulated VL vs Standard DL in Surgical Patients]]
+      * **Significance**: More evidence VL is better as first-line?
-    * **Finding**: First-pass intubation failure: hyperangulated VL 1.7% vs DL 7.6%
+    * [[https://doi.org/10.1111/anae.15985 | Mac Geometry VL vs Mac DL]]
-    * **Significance**: More evidence VL is better as first-line?
+      * **Finding:** VL had better first-pass success than DL
-  * [[https://doi.org/10.1097/HEP.0000000000000817 | Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis]]
+  * CARDS
-    * **Finding**: in Child-Pugh B or C with UGIB, TXA improves bleeding control vs placebo
+    * [[https://doi.org/10.1016/j.resuscitation.2024.110360 | IV vs IO for OHCA]]
-  * [[https://doi.org/10.1001/jama.2023.20850 | UK-REBOA]]
+      * Finding: IV assoc with better survival and neuro fav outcomes
-    * **Finding**: In trauma patients with exsanguinating hemorrhage, a strategy of REBOA and standard care in the emergency department does not reduce, and may increase, mortality compared with standard care alone.
+    * [[https://doi.org/10.1056/NEJMoa2307983 | MINT: Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia]]
-  * [[https://doi.org/10.1056/NEJMoa2307983 | MINT: Restrictive or Liberal Transfusion Strategy in Myocardial Infarction and Anemia]]
+      * **Finding**: In patients with acute myocardial infarction and anemia, a liberal transfusion strategy did not significantly reduce the risk of recurrent myocardial infarction or death at 30 days.
-    * **Finding**: In patients with acute myocardial infarction and anemia, a liberal transfusion strategy did not significantly reduce the risk of recurrent myocardial infarction or death at 30 days.
+  * CCM
-  * [[https://doi.org/10.1111/anae.15985 | Mac Geometry VL vs Mac DL]]
+    * [[https://dx.doi.org/10.1056/NEJMoa2516567 | HI-PEITHO for intermediate risk PE]]
-    * **Finding:** VL had better first-pass success than DL
+    * [[http://doi.org/10.1056/NEJMoa2502136 | No Art Line in Shock]]
+    * [[https://doi.org/10.1056/NEJMoa2404245 | Pantoprazole for MV GI bleed ppx]]
+      * **Finding**: reduces GIB, no mortality benefit
+      * [[https://doi.org/10.1097/CCM.0000000000006376 | Calcium for hyperK]]
+      * **Finding**: not via membrane stabilization
+  * MCS
+    * [[https://doi.org/10.1056/NEJMoa2312572 | DANGER-SHOCK]]
+      * **Finding**: Impella CP reduces mortality
+      * **Significance**: First trial to show mortality benefit from MCS
+  * MV
+    * [[https://doi.org/10.1164/rccm.202503-0544OC | SBT respiratory mechanics to predict re-intubation]]
+      * in reintubation group, normalized compliance declined and inspiratory effort increased. in non-reintubated group, $C_{norm}$ and $E_{insp}$ unchanged throughout SBT
+  * PULM
+    * [[https://doi.org/10.1056/NEJMoa2507100 | Steroids in Non-Severe CAP]]
+    * [[https://doi.org/10.1056/NEJMoa2411664 | brensocatib for bronchiectasis]]
+    * [[ https://www.nejm.org/doi/full/10.1056/NEJMoa2406673 | Depemokimab]]
+    * [[https://www.nejm.org/doi/full/10.1056/NEJMoa2409712 | Inebilizumab for Treatment of IgG4-Related Disease]]
+  * GI
+    * [[https://doi.org/10.1097/HEP.0000000000000817 | Tranexamic acid in upper gastrointestinal bleed in patients with cirrhosis]]
+      * **Finding**: in Child-Pugh B or C with UGIB, TXA improves bleeding control vs placebo
+  * Trauma
+    * [[https://doi.org/10.1001/jama.2023.20850 | UK-REBOA]]
+      * **Finding**: In trauma patients with exsanguinating hemorrhage, a strategy of REBOA and standard care in the emergency department does not reduce, and may increase, mortality compared with standard care alone.

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