====== SSc-ILD ====== * GAP score * [[https://doi.org/10.1093/rheumatology/keaf445 | ILD-RISC score]] * Outcome to predict: the presence of ILD on HRCT * score: a probability (0 to 1.0) * ILD-RISC score >= 0.3 had sensitivity 85.6% and specificity 53.6% * items: * age * ever had digital ulcers (OR 2.06) * DLCO * FVC * antibody (topo I: OR 2.38, PM/SCL: 2.56, RNAPIII: 1.41) ====== IIM-ILD ====== ===== FLAIR model ===== * [[https://doi.org/10.1016/j.chest.2020.04.057 | article]] * bottom line: MDA5 is bad, high inflammatory markers are bad, l ^item^categorical_value^score^ | ferritin | >= 636 ng/mL | TRUE: 2, FALSE: 0| | LDH | >= 355 U/L | TRUE: 2, FALSE: 0| | anti-MDA5 antibody | >= 636 ng/mL | negative, 0; +, 2; ++, 3; +++, 4| | high-resolution CT imaging score (as described by https://doi.org/10.1164/rccm.2106157)| >= 133 | TRUE: 3, FALSE: 0 | * Scoring * low, 0 to 4 * medium, 5 to 9 * high, 10 to 13 ===== CROSS model ===== ^boolean parameter^ $\beta$ coefficient ^ score ^ | CRP abnormal | 0.754 | 1 | | Anti-Ro52 positivity | 1.505 | 2 | | male sex | 0.624 | 1 | | disease duration <3 months | 1.291 | 2 | ^ risk strata ^ qualifying scores ^ | moderate | 0-2 | | high | 3-4 | | very high | 5-6 | ===== RRP model ===== ^boolean parameter^score if TRUE^ | fever | 5| | periungual erythema | 6| | elevated CRP | 5 | | anti-MDA5 antibody | 8 | | anti-Ro-52 antibody | 6 | ^ risk strata ^ qualifying scores ^ | moderate | 0-9 | | high | 10-19 | | very high | 20-30 |