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**This is an old revision of the document!**
Table of Contents
- Primary Outcomes
- Secondary Outcomes
- Reported Result
- “When compared with AC alone, CDT had lower mortality but high major bleeding and numerically higher ICH”
- “The risk of morality and ICH was high with ST when compared with CDT.
- Findings were similar when analysis was restricted to intermediate risk PE.
Problems
The Definition of Risk Groups is not Stated
- Uses “intermediate risk,” “high risk”, and “intermediate-high risk,” thus mixing terminologies
- 2019 ESC: low, intermediate-low, intermediate-high, high
- 2011 AHA: massive, sub-massive, low risk
- 2016 CHEST: low high, PE without hypotension, PE with hypotension
Very few RCT patients got CDT
| Total Papers (n=45) | ||
|---|---|---|
| patient_type | number | percent |
| AC | 19976 | 24.4% |
| CDT | 9610 | 11.8% |
| ST | 52119 | 63.8% |
| total | 81705 | NA |
| Intermediate-Risk Papers (n=20) | ||
|---|---|---|
| patienttype^number^percent^ |AC|8873|75.9%| |CDT|1929|16.5%| |ST|883|7.5%| |total|11685|14.3% (of $n{total}$) | ||
| RCT Trials Only (n=17) | ||
|---|---|---|
| patienttype^number^percent^ |AC|1101|49.8%| |CDT|78|3.5%| |ST|1031|46.7%| |total|2210|2.7% (of $n{total}$) | ||
This means that the number of CDT patients from RCTs is only $\frac{n{CDT}}{n{total}}=\frac{78}{81611}=0.096\%$ of the study total!!
The Primary Outcome is not reported correctly
jc.1713918614.txt.gz · Last modified: 2024/04/24 00:30 by admin
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